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Dr Keith Ballingall

Dr Keith Ballingall

Moredun Research Institute
Pentlands Science Park
Bush Loan
Penicuik
Midlothian EH26 0PZ

Biography

Keith's research interests are in molecular immunology and immunogenetics with a focus on genes and proteins in livestock populations controlling recognition and the responses to infection.  His current research is directed towards the development and application of an MHC defined sheep resource flock.  Such a resource will have a wide range of applications in defining the mechanisms of natural immunity and the identification of those pathogen antigens which stimulate protective responses.  These may then be fed into the vaccine development pathway.  Keith's additional interests are in the areas of genetics of disease resistance and the development of genotyping methodologies.

Current Research

  • Keith is currently responsible for the development and curation of the immunopolymorphism database(IPD-MHC) for genes and alleles at MHC loci of sheep species and chairs the International Society for Animal Genetics/International Union of Immunological Societies Comparative MHC Nomenclature Committee.
  • Additional projects focus on characterising current levels of MHC diversity in UK, European and African sheep breeds and analysing links between MHC genetic diversity and resistance and susceptibility to infectious diseases of sheep.

Selected Key Publications