Dr Clare Hamilton

clare.hamilton@moredun.ac.uk

Moredun Research Institute
Pentlands Science Park
Bush Loan
Penicuik
Midlothian EH26 0PZ

Biography

Clare received her undergraduate degree in Zoology from the University of Edinburgh (2000) before joining Moredun as a research assistant in parasitology.

Whilst in that role, Clare completed a Masters by Research (University of Edinburgh; 2003) on Cryptosporidium parvum in shellfish. She went on to gain a PhD (Trinity College Dublin; 2005) in research on Toxocara canis before taking up a postdoc position (Dublin City University; 2005-2008) working on liver fluke. Following this, she held a lecturing position at University College Dublin (2008-2012) teaching parasitology and immunology to veterinary students.

Clare joined Moredun in 2013 and managed a collaborative research project with Ross University School of Veterinary Medicine in St. Kitts (West Indies) investigating the epidemiology and genetic diversity of T. gondii in the Caribbean. This sparked her interest in pathogen virulence and has led to her current focus on the role of host and pathogen in characterising T. gondii virulence. Clare is also interested in food safety, particularly foodborne toxoplasmosis (she is a registered specialist with the FSA).

Clare is also part of EPIC, where her work focuses on Cryptosporidium spp. and how molecular profiling can inform on potential transmission routes of the parasite at farm-level.

ORCID profile: https://orcid.org/0000-0002-2101-5194

Current Research

Current research, funded by a BBSRC-FAPESP responsive mode grant (2020-2023), focuses on characterising T. gondii virulence using cells and enteroids from ovine, murine and human hosts. This is in collaboration with University of São Paulo, Biomathematics and Statistics Scotland (BioSS) and Newcastle University.
Investigating the incidence, viability and genetic diversity of T. gondii in retail meat samples in Scotland (Scottish Government Strategic Research Programme 2016-2021).
Molecular epidemiology and transmission dynamics of Cryptosporidium spp: detection, speciation and typing of isolates from environmental samples (water samples as well as faecal material from livestock and wildlife) generated from catchment areas (EPIC).
Involved in investigating causes of mortality, abortion and reproductive losses of cattle and small ruminants in Tanzania (SEBI-TZ project; University of Glasgow).

Selected Key Publications

de Melo, R.Pimentel B., Wanderley, F.Santos, Porto, W.José Nasc, Pedrosa, Cde Morais, Hamilton, C.M., de Oliveira, M.Heloísa G., Ribeiro-Andrade, M., Rêgo, R.Camila da, Katzer, F., Mota, R.A. 2020. Description of an atypical Toxoplasma gondii isolate from a case of congenital toxoplasmosis in northeastern Brazil Parasitology Research 119():2727-2731.
Plaza, J., Dámek, F., Villena, I., Innes, E.A., Katzer, F., Hamilton, C.M. 2020. Detection of Toxoplasma gondii in retail meat samples in Scotland Food and Waterborne Parasitology 20():e00086.
Semango, G., Hamilton, C.M., Kreppel, K., Katzer, F., Kibona, T., Lankester, F., Allan, K.J., Thomas, K.M., Claxton, J.R., Innes, E.A., Swai, E.S., Buza, J., Cleaveland, S., De Glanville, W.A. 2019. The sero-epidemiology of Neospora caninum in cattle in Northern Tanzania Frontiers in Veterinary Science 6():327.
Hamilton, C.M., Robins, R., Thomas, R., Oura, C., Oliveira, S., Villena, I., Innes, E.A., Katzer, F., Kelly, P.J. 2019. Prevalence and genetic diversity of Toxoplasma gondii in free-ranging chickens from the Caribbean Acta Parasitologica 64():738-744.
Innes, E.A., Hamilton, C., Garcia, J.L., Chryssafidis, A., Smith, D. 2019. A One Health approach to vaccines against Toxoplasma gondii Food and Waterborne Parasitology 15():e00053.
Hamilton, C.M., Black, L., Oliveira, S., Burrells, A., Bartley, P.M., Melo, R.Pimentel B., Chianini, F., Palarea-Albaladejo, J., Innes, E.A., Kelly, P.J., Katzer, F. 2019. Comparative virulence of Caribbean, Brazilian and European isolates of Toxoplasma gondii Parasites & Vectors 12():104.
Hamilton, C.M., Kelly, P.J., Boey, K., Corey, T.M., Huynh, H., Metzler, D., Villena, I., Su, C., Innes, E.A., Katzer, F. 2017. Predominance of atypical genotypes of Toxoplasma gondii in free-roaming chickens in St. Kitts, West Indies Parasites & Vectors 10():104.
Hamilton, C.M., Kelly, P.J., Bartley, P.M., Burrells, A., Porco, A., Metzler, D., Crouch, K., Ketzis, J.K., Innes, E.A., Katzer, F. 2015. Toxoplasma gondii in livestock in St. Kitts and Nevis, West Indies Parasites & Vectors 8():166.
Hamilton, C.M., Katzer, F., Innes, E.A., Kelly, P.J. 2014. Seroprevalence of Toxoplasma gondii in small ruminants from four Caribbean islands Parasites & Vectors 7():449.
Hamilton, C.M., Katzer, F., Beierschmitt, A., Soto, E., Innes, E.A., Kelly, P.J. 2014. First report of Toxoplasma gondii seroprevalence in wild-caught Caribbean African green monkeys Parasites & Vectors 7():571.

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Dr Clare Hamilton

Biography

Current Research

Selected Key Publications

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