Professor Jacqui Matthews
Moredun Research Institute
Pentlands Science Park
Midlothian EH26 0PZ
After qualifying in veterinary medicine at the University of Glasgow, Jacqui’s career has been in helminthology research. Her research spans immunology, vaccine development and diagnostics to support sustainable worm control in ruminants and horses. She has obtained over £13 million in competitive grant funding to support her research and has published >120 associated peer-reviewed research papers. In addition to support from Scottish Government, her research has been/is funded by BBSRC, Wellcome Trust, DEFRA-VMD, Horserace Betting Levy Board, Horse Trust, Pilkington Trust, Donkey Sanctuary, Perry Foundation, animal health companies and EU H2020.
Currently, Jacqui is Coordinator a 9 million euro EU Horizon 2020 project, PARAGONE, which brings together 17 scientific and industrial partners from across the globe to develop vaccines for multicellular parasites. She is also Principal Investigator on helminthology projects funded by DEFRA/VMD, the BBSRC and the Horse Trust. She holds a ministerial appointment on the UK Veterinary Products Committee, with membership of committees on parasite control guidelines, animal welfare trustee boards, the BBSRC Pool of Experts and journal editorial boards. She lectures and examines at several UK veterinary schools and regularly provides seminars on worm control to farmers, horse owners, SQPs, veterinarians and other stakeholders. She has a strong commitment to post-graduate teaching and is Chair of Moredun’s Post-graduate Committee.
Jacqui holds an Honorary Professorship at the Royal (Dick) School of Veterinary Studies, University of Edinburgh, and is Translational Facilitator of the University of Edinburgh’s Centre of Immunity, Infection and Evolution (http://ciie.bio.ed.ac.uk/).
2015-19 EU (Horizon 2020). PARAGONE: vaccines for animal parasites. Principal Investigator & Coordinator, 17 partners. €8,998,500.
2015-18 BBSRC. Dissecting variation in host immune responsiveness to a recombinant vaccine designed to control teladorsagiosis. Principal Investigator, with AJ Nisbet, TN McNeilly, S Burgess (Moredun), S Babyan (Glasgow). £612,089.
2015-18 Horse Trust. Taking evidence-based control into the field: tools and training initiatives aimed at mitigating helminth-associated disease in horses. Principal Investigator, with JE Hodgkinson (Liverpool), ER Morgan (Bristol), S Burgess (MRI). £198,196.
2014-16 BBSRC Super Follow-on Fund. Technical development of a novel vaccine vehicle for cattle pathogens. Co-investigator with KR Matthews (PI, Edinburgh). £301,483.
2013-16 DEFRA/Veterinary Medicines Directorate. A study to consider prescribing groups and distribution channels to ensure appropriate use of anthelmintics in the UK. Principal Investigator, with JE Hodgkinson & G Pinchbeck (Liverpool). £266,364.
2013-16 Horserace Betting Levy Board. Development of tools to promote best practice parasite control on Thoroughbred studs. Co-investigator, with JE Hodgkinson (PI, Liverpool). £122,465.
She also has commercial funding for vaccine development work.
A selection of Jacqui's publications can be seen below or for a fuller list please click here.
Selected Key Publications
- Mitchell, M. C., Tzelos T., Handel I., McWilliam H. E. G., Hodgkinson J. E., Nisbet A. J., et al. 2016. Development of a recombinant protein-based ELISA for diagnosis of larval cyathostomin infectionSUMMARY. Parasitology. 143(08):1055 - 1066.
- Easton, S., Bartley D. J., Hotchkiss E., Hodgkinson J. E., Pinchbeck G. L., & Matthews J. B. 2016. Use of a multiple choice questionnaire to assess UK prescribing channels’ knowledge of helminthology and best practice surrounding anthelmintic use in livestock and horses. Preventive Veterinary Medicine. 128():70 - 77.
- Matthews, J. B. 2014. Anthelmintic resistance in equine nematodes. International Journal for Parasitology: Drugs and Drug Resistance.
- Relf, V. E., Lester H. E., Morgan E. R., Hodgkinson J. E., & Matthews J. B. 2014. Anthelmintic efficacy on UK thoroughbred stud farms. International Journal for Parasitology. 44(8):507 - 514.
- Nisbet, A. J., McNeilly T. N., Wildblood L. A., Morrison A. A., Bartley D. J., Bartley Y., et al. 2013. Successful immunization against a parasitic nematode by vaccination with recombinant proteins. Vaccine. 31(37):4017-4023.
Not a Member?
Moredun membership allows you to keep up to date with the latest advances in livestock health. You can join or renew your Moredun membership online.