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Immunopolymorphism Database

Research

Moredun's MHC defined flock comprises animals homozygous for one of four common MHC haplotypes along with a large number of matched MHC heterozygous animals.  Each of the MHC haplotypes has been extensively characterised at the genetic level with the important MHC class I and class II genes cloned, sequenced and expressed. 

These sequences have provided the reference sequences for populating the sheep section of the immunopolymorphism database [1].  This public database provides a source of information on MHC genetic diversity in domestic sheep. Its purpose is to collate data on allelic diversity and provide a forum for the analysis, verification and nomenclature of diversity in the genes and proteins of the ovine MHC.

Related staff: 
Dr Keith Ballingall [2]
1. External Link Title: 
Immunopolymorphism Database
1. External Link: 
http://www.ebi.ac.uk/ipd/mhc/ovar/index.html

Source URL: http://www.moredun.org.uk/research/expertise-%40-moredun/epidemiology-%2526-population-biology/mhc-defined-flock/immunopolymorphism-database

Links:
[1] http://www.ebi.ac.uk/ipd/mhc/ovar/index.html
[2] http://www.moredun.org.uk/staff/dr-keith-ballingall